Source: money.ca.msn.com --- Tuesday, July 30, 2013
NEW YORK, N.Y. - The price of oil closed at a four-week low Tuesday as traders awaited comments from the U.S. central bank as well as data releases later in the week, including U.S. Jobs figures. ...
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Source: http://girlsbestphriend.wordpress.com/2013/07/31/for-the-phillies-theres-no-place-like-home/
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Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/qDBd4_nfysA/130731104142.htm
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I have been searching here and on Google but have not found the information I am looking for.
I have a copy of the windows version of Microsoft Office 2007 and was planning on installing it on my new 13" rMBP via Crossover as an alternative to using parallels. Questions I have before doing so:
1. How does Office perform via Crossover?
2. How would the software look on the retina screen? I.E. does it look bad/blurry as I doubt it is optimized for the higher resolution screen?
3. Would all functions of the software perform as it would in Windows? Such as Excel plug-ins, etc. Also, how does the installation of plug ins work?
Crossover sounds like a better option to me because I will not be using any other windows software and I would save a decent amount of space on the SSD (please correct me if this is not true).
Thanks!
Source: http://forums.macrumors.com/showthread.php?t=1616368&goto=newpost
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Source: http://www.extranewspapers.co.uk/features/extra-pets/kidney-disease-in-cats-spot-the-warning-signs/
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WASHINGTON (AP) ? With a cast of characters that has presided over numerous failed Middle East peace efforts, the Obama administration launched a fresh bid Monday to pull Israel and the Palestinians into substantive negotiations.
Despite words of encouragement, deep skepticism about the prospects for success surrounded the initial discussions, which were opening with a dinner hosted by Secretary of State John Kerry. He named a former U.S. ambassador to Israel to shepherd what all sides believe will be a protracted and difficult process.
Former envoy Martin Indyk, who played key roles in the Clinton administration's multiple, unsuccessful pushes to broker peace deals between Israel and Syria and Israel and the Palestinians, will assume the day-to-day responsibility for keeping the talks alive for the next nine months.
Kerry called Indyk a "seasoned diplomat" and said he "knows what has worked and he knows what hasn't worked." Neither Kerry nor the State Department would say what has worked in the past, although the fact that there is no peace deal now would seem to indicate that nothing has worked in resolving the Israeli-Palestinian standoff.
President Barack Obama echoed Kerry's hopeful sentiment in a White House statement that said Indyk "brings unique experience and insight to this role, which will allow him to contribute immediately as the parties begin down the tough, but necessary, path of negotiations."
The Israeli side will be led by chief negotiator Tzipi Livni, a former foreign minister who was active in the Bush's administration's ill-fated Annapolis peace talks with the Palestinians, and Yitzhak Molcho, a veteran adviser to Prime Minister Benjamin Netanyahu who was part of the Israeli team involved in Obama's two previous attempts to broker negotiations. Those two efforts relied heavily on Dennis Ross, a former Indyk colleague and Mideast peace envoy, and veteran negotiator George Mitchell.
The Palestinian team will be led by chief negotiator Saeb Erekat and President Mahmoud Abbas' adviser, Mohammed Shtayyeh, both of whom have been major players in failed negotiations with the Israelis since 1991.
Kerry spoke for about 45 minutes with representatives from the Israeli negotiating team and then another roughly 45 minutes with the Palestinian side before sitting down for dinner on the top floor of the State Department.
"Not very much to talk about at all," Kerry joked just before starting dinner shortly after 9 p.m.
They sat at a rectangular table ? five U.S. officials lining one side and the two Israeli and two Palestinian negotiators on the other ? to dine on sweet corn and shell bean soup, grilled grouper, saffron risotto, summer vegetables and apricot upside down cake.
Despite the presence of so many people whose past experience does not include success, Kerry and other officials voiced cautious optimism about the resumption of talks which he painstakingly negotiated during six months of shuttle diplomacy that began with Obama's own trip to Israel in March.
"It sounds like we're lucky to have decades of experience ready to come back to the table and make an effort to push forward," State Department spokeswoman Jen Psaki said.
Previous attempts to get talks started have foundered on Israel's continued construction of Jewish settlements on land claimed by the Palestinians and Palestinian attempts to win international recognition as a sovereign state in the absence of a peace deal. Actual negotiations have died because the two sides have been unable to compromise on the most serious disagreements between them: borders, the status of Jerusalem, refugees and security.
With a U.S.-imposed gag order on revealing any details about the substance or framework of the talks, gauging progress will be difficult. But the outlines of any eventual peace deal are fairly well known: a Palestinian state based on the lines that existed before the 1967 war in which Israel seized east Jerusalem and occupied the Palestinian territories, with agreed land swaps and recognition of a secure, Jewish state of Israel.
But neither side will publicly commit to those goals, and getting there will require major concessions that will be difficult to sell to the Israeli and Palestinian publics.
Ahead of the initial discussions on procedures and guidelines for the meetings, which the U.S. hopes will grow into deeper, more substantive talks on the key sticking points, Kerry urged both sides to strive for "reasonable compromises on tough, complicated, emotional and symbolic issues."
He acknowledged that the path ahead would be long and difficult. But he said that Indyk had the respect and confidence of all involved and that his vast experience in Middle East diplomacy could only help.
"Ambassador Indyk is realistic," Kerry said. "He understands that Israeli-Palestinian peace will not come easily and it will not happen overnight. But he also understands that there is now a path forward and we must follow that path with urgency. He understands that to ensure that lives are not needlessly lost, we have to ensure that opportunities are not needlessly lost."
Indyk, 62, will take a leave of absence from his current job as vice president and foreign policy director at the Washington-based Brookings Institution think tank.
In announcing Indyk's appointment, Kerry noted the former ambassador had opened the preface to his 2009 book, "Innocent Abroad: An Intimate Account of American Peacemaking Diplomacy in the Middle East," with lines from the English poet Samuel Taylor Coleridge.
"If men could learn from history, what lessons it would teach us," Kerry quoted.
He did not continue to the next lines as Indyk did in his book:
"But passion and party blind our eyes,"
"And the light which experience gives us is a lantern on the stern,"
"Which shines only on the waves behind us."
___
Associated Press writer Deb Riechmann contributed to this report.
Source: http://news.yahoo.com/familiar-cast-us-launches-mideast-peace-bid-210135306.html
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Google has rolled out its Google Translate handwriting feature for the web, allowing users to draw the phrases or words they need translated when a keyboard can't do the trick.
Handwriting has been an option on the Google Translate Android app since January 2012, but it is now available via the Google Translate website on the browser.
Imagine planning a trip to China, but not being able to read street signs or restaurant names. Instead of blindly choosing a direction or eatery, just draw the given characters on the Google Translate homepage to find their meaning.
To get started, choose the language you wish to translate, and then select the down arrow on the bottom left of the language box. Select the "Handwrite" option with the pencil and draw away in the pop-up box that appears.
"Suppose you see the Chinese expression '??' and want to know its meaning in English, but have no idea how to type these characters," Google product manager Xiangye Xiao said in a blog post. "Using the new handwriting input tool, you can simply draw these characters on your screen and instantly see the translation."
You can draw with your mouse, or with your finger if you have a touch-enabled PC.
Google Translate currently supports handwriting in 45 languages, including Chinese, Japanese, and Korean.
Other text input tools like virtual keyboards, input method editors, and transliteration were added to Translate early last year.
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North Korean war veterans of the Korean War watch the 'Arirang' mass games song-and-dance ensemble at the May Day stadium, Friday, July 26, 2013 on the eve of the 60th anniversary of the Korean War armistice in Pyongyang, North Korea. (Wong Maye-E/AP)
Soviet Ambassador to the United Nations Jacob Malik first proposed a cease-fire in 1951, and the first negotiations began in July of that year at Kaesong. However, talks broke down in 1952 over the issue of how to deal with prisoners of war. Meanwhile, hostilities continued. It wasn?t until April of 1953 that the issue was resolved and an agreement was reached and signed in July. Though South Korea refused to sign, fighting ended soon after.
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is there any difference between for example controlled labs fish oil and just regular fish oil that i can buy in regular stores in my country ( the netherlands)and is creatine usefull for a 16 year old?
EDIT: about the creatine i train 4 times a week.
Hi Willem,Visolie van Marinol is erg goed en niet duur.
360 capsules voor 19,90 bij body en fit shop.Creatine is made in your body and is present in meat and fish.
How long are you training?
Hi Willem,Visolie van Marinol is erg goed en niet duur.
360 capsules voor 19,90 bij body en fit shop.Creatine is made in your body and is present in meat and fish.
How long are you training?
im training for 8 months now i guess but since 3 months im also eating right and things like that.so you mean i dont need creatine?
1)Yes there is a difference between CL fish oil with other brands.CL has 2000mg Omega 3 whereas most regular ones have 1000mg or so
2)No you don't need creatine for now.Eat healthy food and you'll be fine.
1)Yes there is a difference between CL fish oil with other brands.CL has 2000mg Omega 3 whereas most regular ones have 1000mg or so
2)No you don't need creatine for now.Eat healthy food and you'll be fine. okay thankyou!!
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Jul 26, 2013 - 01:34 PM EDT ? AAPL: 439.111 (+0.611, +0.14%) | NASDAQ: 3587.615 (-23.662, -0.66%)
?A new image has emerged claiming to show Apple?s low-cost plastic iPhone in the wild, bearing the required legal notices from the FCC and other agencies,? Kevin Bostic reports for AppleInsider.?The new image appeared on Chinese site Weibo (via iPhone5skopen) on Friday, and it shows a back view of the supposed ?iPhone Lite? in the hand of the photographer,? Bostic reports. ?The object seen in the image bears what look like notices and markings from the FCC and assorted other certifications. ?
Bostic reports, ?Previous views of the supposed Apple device have shown the casing only with the word iPhone, but not with any certification markings.?
Apple?s low-cost iPhone? (image via: iPhone5skopen)
?
Read more in the full article here.
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The roots of obesity are complex and include genetics and other factors beyond individual choice, research shows.
iStockphoto.comDon't try to pretend your gibes and judgments of the overweight people in your life are for their own good. Florida researchers have evidence that discriminating against fat people only makes them fatter.
"People often rationalize that it's OK to discriminate based on weight because it will motivate the victim to lose pounds," Angelina Sutin, a psychologist at the Florida State College of Medicine in Tallahassee, tells Shots. "But our findings suggest the opposite."
Sutin and a colleague checked survey data from more than 6,000 American men and women age 50 and older who were asked how often in their daily lives they experienced different types of discrimination. Examples ranged from discourtesy or refusal of restaurant service to not getting a job or promotion.
The survey then asked the respondents why they thought the discrimination happened. Was it was because of their race or age, for example, or their sex, age or weight? Researchers also measured the participants' weight and height.
Four years later, a follow-up survey asked the same questions and checked for changes in weight.
Overweight people who said they'd experienced discrimination based on weight were more than twice as likely to be obese four years later than people who didn't mention such discrimination. And those who started out obese were three times more likely to remain so if they'd been harshly targeted because of their weight. Other types of discrimination showed no effect on weight.
Sutin's study, published in the latest issue of the online journal PLOS One, wasn't designed to get at why weight discrimination led many fat people to pack on even more pounds. But other research suggests that increased rates of depression, emotional eating and low-self esteem likely play a role. So does increased stress (and the associated hormonal surges that can trigger even more hunger and eating), as well as the avoidance of exercise.
"If someone's mean to you at the gym because of your weight or acts like you don't belong there," Sutin says, "you're less likely to go back."
The roots of obesity are complex and include genetics and other factors that go well beyond individual choice. "Trying to promote healthy behaviors is a good thing," she says, but shaming someone has no place in the solution.
Unfortunately, weight-related prejudice and discrimination persists in many spheres and is only increasing among employers, teachers ? and doctors.
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Highest paid: David Guzick, University of Florida senior VP of health affairs and president of UF Health.
It?s good to work for Gator Nation, especially if you?re one of the 471 University of Florida employees pulling down over $200,000 a year.
UF has the most high-salaried employees of any state university in Florida, according to figures taken from state data for Spring 2013. In fact, 2,031 of its employees made at least $100,000.
Click here for a list of the Top 50 highest paid employees at UF. Most of them work for its College of Medicine. The lone exception is an eminent scholar and professor of finance who has testified before Congress.
Check out the slideshow of the ten highest paid UF employees at the South Florida Business Journal. All of them are in the medical field.
You won?t find UF President James Bernie Machen in the Top 50, but there?s a caveat. He earned $238,529 from contracts and grants and another $199,943 from education and general funds to count as two entries. That still trails some of the medical gurus. Hey, running a university apparently isn?t brain surgery.
Click here for a searchable database of all UF employees.
That doesn?t include the salaries of coaches, who weren?t included in the state data file. For the record through, basketball coach Billy Donovan makes $3.3 million and football coach Will Muschamp makes $2.7 million.
Brian Bandell covers banking, finance, health care and education. Get the latest banking industry news here.
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AP
A Palestinian man looks out over buildings in the Rafah refugee camp destroyed by Israeli airstrikes, southern Gaza Strip.
Israel and Palestine must make every effort to resume talks on a negotiated settlement, leaders in the Church of England and Roman Catholic Church have said.
The call came in a joint statement from the Church of England's lead bishop on the Middle East peace process, Bishop Michael Langrish, and the Roman Catholic Church's spokesman on international affairs, Bishop Declan Lang.
US Secretary of State John Kerry announced last week that Israeli and Palestinian leaders had reached an agreement establishing a basis for the resumption of peace talks.
The bishops appealed to both sides of the conflict to take full advantage of the opportunity for fresh talks and "refrain from actions that might see this chance lost".
"This conflict has for far too long been an open wound that has frustrated the hopes and aspirations of both communities to live in dignity, peace and security," they said.
"Now is the time to escape the prism of pain and fear through which Christian, Jew and Muslim see each other in the Holy Land."
They added: "The prospect for securing a negotiated resolution has never looked so daunting but neither has it been so necessary. The cost of failure is too unbearable to imagine."
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Public release date: 24-Jul-2013
Share ] Contact: Catherine Kolf
ckolf@jhmi.edu
443-287-2251
Johns Hopkins Medicine
David Foster, Ph.D., an assistant professor of neuroscience at the Johns Hopkins University School of Medicine, will be awarded the 2013 Freedman Prize Honorable Mention for Exceptional Basic Research at an awards ceremony in New York City on July 26. The prize will be awarded by the Brain & Behavior Research Foundation, the oldest U.S. nonprofit to support a broad range of mental health research. Foster is a grantee of the foundation and the award is meant to honor him as an early-career researcher contributing exceptional, cutting-edge work to the mental health field.
"David is a very creative scientist with a passion for his work, and I am glad he is being recognized by the Brain & Behavior Research Foundation for his exceptional research," says Richard Huganir, Ph.D., professor and director of the Solomon H. Snyder Department of Neuroscience.
Foster is being recognized for his work, and the innovative tools he developed, to study the neural basis of memory. His work focuses on nerve cells in the hippocampus region of the brain. Damage to the hippocampus disrupts specific types of memory and learning in people with Alzheimer's disease and age-related cognitive decline. Foster has combined advanced electrophysiological, computational and behavioral approaches to investigate the coordinated activity of large numbers of hippocampal nerve cells in rats that are awake and engaged in tasks, like finding their way back to a familiar location. Foster's work suggests that the processes used by the brain to do these simple tasks are similar to those used in higher-order brain functions, like problem-solving.
###
Related Stories:
Rat Brain 'GPS' Maps Routes to Rewards: http://www.hopkinsmedicine.org/news/media/releases/rat_brain_gps_maps_routes_to_rewards
Foster Discusses His Results with the Johns Hopkins Brain Science Institute: http://www.new.prx.org/pieces/98923-brain-talk-029-foster/floating_piece
Foster Discusses His Results with Nature (minute 7): http://www.new.prx.org/pieces/98923-brain-talk-029-foster/floating_piece
Johns Hopkins Medicine
Media Relations and Public Affairs
Media Contacts:
Catherine Kolf
443-287-2251
ckolf@jhmi.edu
Vanessa McMains
410-502-9410
vmcmain1@jhmi.edu
Shawna Williams
410-955-8236
shawna@jhmi.edu
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 24-Jul-2013 Share ] Contact: Catherine Kolf
ckolf@jhmi.edu
443-287-2251
Johns Hopkins Medicine
David Foster, Ph.D., an assistant professor of neuroscience at the Johns Hopkins University School of Medicine, will be awarded the 2013 Freedman Prize Honorable Mention for Exceptional Basic Research at an awards ceremony in New York City on July 26. The prize will be awarded by the Brain & Behavior Research Foundation, the oldest U.S. nonprofit to support a broad range of mental health research. Foster is a grantee of the foundation and the award is meant to honor him as an early-career researcher contributing exceptional, cutting-edge work to the mental health field.
"David is a very creative scientist with a passion for his work, and I am glad he is being recognized by the Brain & Behavior Research Foundation for his exceptional research," says Richard Huganir, Ph.D., professor and director of the Solomon H. Snyder Department of Neuroscience.
Foster is being recognized for his work, and the innovative tools he developed, to study the neural basis of memory. His work focuses on nerve cells in the hippocampus region of the brain. Damage to the hippocampus disrupts specific types of memory and learning in people with Alzheimer's disease and age-related cognitive decline. Foster has combined advanced electrophysiological, computational and behavioral approaches to investigate the coordinated activity of large numbers of hippocampal nerve cells in rats that are awake and engaged in tasks, like finding their way back to a familiar location. Foster's work suggests that the processes used by the brain to do these simple tasks are similar to those used in higher-order brain functions, like problem-solving.
###
Related Stories:
Rat Brain 'GPS' Maps Routes to Rewards: http://www.hopkinsmedicine.org/news/media/releases/rat_brain_gps_maps_routes_to_rewards
Foster Discusses His Results with the Johns Hopkins Brain Science Institute: http://www.new.prx.org/pieces/98923-brain-talk-029-foster/floating_piece
Foster Discusses His Results with Nature (minute 7): http://www.new.prx.org/pieces/98923-brain-talk-029-foster/floating_piece
Johns Hopkins Medicine
Media Relations and Public Affairs
Media Contacts:
Catherine Kolf
443-287-2251
ckolf@jhmi.edu
Vanessa McMains
410-502-9410
vmcmain1@jhmi.edu
Shawna Williams
410-955-8236
shawna@jhmi.edu
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2013-07/jhm-dfa072413.php
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This image taken from security camera video shows a train derailing in Santiago de Compostela, Spain, on Thursday July 25, 2013. Spanish investigators tried to determine Thursday why a passenger train jumped the tracks and sent eight cars crashing into each other just before arriving in this northwestern shrine city on the eve of a major Christian religious festival, killing at least 77 people and injuring more than 140. (AP Photo)
This image taken from security camera video shows a train derailing in Santiago de Compostela, Spain, on Thursday July 25, 2013. Spanish investigators tried to determine Thursday why a passenger train jumped the tracks and sent eight cars crashing into each other just before arriving in this northwestern shrine city on the eve of a major Christian religious festival, killing at least 77 people and injuring more than 140. (AP Photo)
This image taken from security camera video shows a train derailing in Santiago de Compostela, Spain, on Thursday July 25, 2013. Spanish investigators tried to determine Thursday why a passenger train jumped the tracks and sent eight cars crashing into each other just before arriving in this northwestern shrine city on the eve of a major Christian religious festival, killing at least 77 people and injuring more than 140. (AP Photo)
Relatives of victims involved in a train accident react at a victims information point in Santiago de Compostela, Spain, on Thursday July 25, 2013. Relatives of victims from a train crash in northwestern Spain sobbed and hugged each other Thursday near a makeshift morgue in a sports arena for the victims as the death toll rose to 78 and investigators tried to determine the cause. The train jumped the tracks and at least one passenger told a radio station that it appeared to be going very fast as it went into a pronounced curve while approaching the station in this Catholic shrine city on the eve of a major religious festival. (AP Photo/Brais Lorenzo)
This combo image taken from security camera video shows clockwise from top left a train derailing in Santiago de Compostela, Spain, on Wednesday July 24, 2013. Spanish investigators tried to determine Thursday why a passenger train jumped the tracks and sent eight cars crashing into each other just before arriving in this northwestern shrine city on the eve of a major Christian religious festival, killing at least 77 people and injuring more than 140. (AP Photo)
Relatives of victims involved in a train accident wait for news at a victims information point in Santiago de Compostela, Spain, on Thursday July 25, 2013. The death toll in a passenger train crash in northwestern Spain rose to 77 on Thursday after the train jumped the tracks on a curvy stretch just before arriving in the northwestern shrine city of Santiago de Compostela, a judicial official said. (AP Photo/Salome Montes)
SANTIAGO DE COMPOSTELA, Spain (AP) ? A Spanish train that hurtled off the rails and smashed into a security wall as it rounded a bend was going so fast that carriages tumbled off the tracks like dominos, killing 80 people, according to eyewitness accounts and video footage obtained Thursday.
An Associated Press analysis of video images suggests that the train may have been traveling at twice the speed limit for that stretch of track.
Spain's government said two probes have been launched into the cause of Wednesday night's crash near this Christian festival city in northwest Spain. The regional government in Galicia confirmed that the train driver, hospitalized in Santiago de Compostela's main hospital with unspecified injuries, was being questioned as a possible suspect but that possible faults in safety equipment were also being investigated.
The Interior Ministry raised the death toll to 80 in what was Spain's deadliest train wreck in four decades. The Galician government said 94 remained hospitalized in six regional hospitals, 31 of them ? including four children ? in critical condition.
The U.S. State Department said one American was killed in the crash and five others were injured. It provided no other details.
Prime Minister Mariano Rajoy, a native of Santiago de Compostela, toured the crash scene alongside rescue workers and went to a nearby hospital to visit those wounded and their families.
"For a native of Santiago, like me, this is the saddest day," said Rajoy, who declared Spain would observe a three-day period of mourning. He said judicial authorities and the Public Works Ministry had launched parallel investigations into what caused the crash.
Eyewitness accounts backed by security-camera footage of the moment of disaster suggested that the eight-carriage train was going too fast as it tried to turn left underneath a road bridge. The train company Renfe said 218 passengers and five crew members were on board. Spanish officials said the speed limit on that section of track is 80 kilometers (50 miles) per hour.
An Associated Press estimate of the train's speed at the moment of impact using the time stamp of the video and the estimated distance between two pylons gives a range of 144-192 kph (89-119 mph). Another estimate calculated on the basis of the typical distance between railroad ties gives a range of 156-182 kph (96-112 mph).
The video footage, which the Spanish railway authority Adif said probably came from one of its cameras, shows the train carriages start to buckle soon into the turn.
Murray Hughes, consultant editor of Railway Gazette International, said it appeared that a diesel-powered unit behind the lead locomotive was the first to derail. The front engine itself quickly followed, violently tipping on to its right side as it crashed into a concrete security wall and bulldozed along the ground.
In the background, all the rear carriages could be seen starting to decouple and come off the tracks. The picture went blank as the engine appeared to crash directly into the camera.
After impact, witnesses said a fire engulfed passengers trapped in at least one carriage, most likely driven by ruptured tanks of diesel fuel carried in the forward engines.
"I saw the train coming out of the bend at great speed and then there was a big noise," one eyewitness who lives beside the train line, Consuelo Domingues, told The Associated Press. "... Then everybody tried to get out of the train."
Santiago officials had been preparing for the city's internationally celebrated Catholic festival Thursday but canceled it and took control of the city's main indoor sports arena to use as a makeshift morgue. There, relatives of the dead could be seen sobbing and embracing each other.
The Interior Ministry, responsible for law and order, ruled out terrorism as a cause.
It was Spain's deadliest train accident since 1972, when a train collided with a bus in southwest Spain, killing 86 people and injuring 112.
"July 24 will no longer be the eve of a day of celebration but rather one commemorating one of the saddest days in the history of Galicia," said Alberto Nunez Feijoo, regional president of Galicia. Santiago de Compostela is its capital.
The accident created a scene that was "Dante-esque," Feijoo said. He said Galicia would observe seven days of mourning.
Rescue workers spent the night searching through smashed carriages alongside the tracks.
As dawn broke, cranes brought to the scene were used to lift the carriages away from the tracks. Rescue workers collected passengers' scattered luggage and loaded it into a truck next to the tracks.
Rescuers described a scene of horror immediately after the crash. Smoke billowed from at least one carriage that had caught fire, while another had been torn into two parts.
Residents of the residential neighborhood closest to the rail line struggled to help victims out of the toppled cars. Some passengers were pulled out of broken windows. Television images showed one man atop a carriage lying on its side, using a pickaxe to try to smash through a window. Other rescuers used rocks to try to free survivors from the fiery wreckage.
Nearby, rescue workers lined up bodies covered in blankets alongside the tracks.
State-owned train operator Renfe said the crash happened at 8:41 p.m. (1841 GMT) about 2.5 miles (4 kilometers) south of Santiago de Compostela.
Spanish media said the train had two drivers aboard and both survived.
However, Galician court officials said the train had only one driver. Court spokeswoman Maria Pardo Rios said the driver survived and was expected to give a statement to police later Thursday. She declined to name the driver.
Renfe said it and Adif, another state-owned company that manages tracks, signals and other railway infrastructure, were cooperating with a judge appointed to investigate the accident.
It was the world's third major rail accident this month.
On July 12, six people were killed and nearly 200 were injured when four cars of a passenger train derailed south of Paris.
On July 6, 72 cars carrying crude oil derailed in Lac-Megantic, Quebec, setting off explosions and fires that killed 47 people.
Catholic pilgrims converge on Santiago de Compostela annually to celebrate a festival honoring St. James, a disciple of Jesus whose remains are said to rest in a shrine. The city is the main gathering point for those who reach the end of the El Camino de Santiago pilgrimage route that has drawn Christians since the Middle Ages.
Several injured passengers said they felt a strong vibration just before the cars jumped the tracks, according to Xabier Martinez, a photographer who talked with them after arriving at the scene as rescue workers were still removing bodies.
One passenger, Ricardo Montero, told the Cadena Ser radio station that "when the train reached that bend it began to flip over, many times, with some carriages ending up on top of others, leaving many people trapped below. We had to get under the carriages to get out."
Another passenger, Sergio Prego, told Cadena Ser the train "traveled very fast" just before it derailed and the cars flipped upside down, on their sides and into the air.
"I've been very lucky because I'm one of the few able to walk out," Prego said.
The Alvia 730 series train started from Madrid and was scheduled to end its journey at El Ferrol, about 95 kilometers (60 miles) north of Santiago de Compostela. Alvias operate high-speed services but do not go as fast as Spain's fastest bullet trains, called AVEs.
The maximum Alvia speed is 250 kph (155 mph) on tracks made especially for the AVEs, and they travel at a maximum speed of 220 kph (137 mph) on normal gauge rails.
Other major train crashes in Spain include a 1944 accident involving three trains that crashed in a tunnel. That disaster produced wildly disputed death tolls ranging from the government's official count of 78 to more than 500, according to later research.
In 2006, 43 people died when a subway train crashed because of excessive speed in the southern city of Valencia. In 2004, 191 died when al-Qaida-inspired terrorists detonated 10 bombs on four Madrid commuter trains.
___
Online: http://www.youtube.com/watch?v=5ywaI50egqk
___
Associated Press writers Alan Clendenning, Ciaran Giles and Harold Heckle in Madrid, Panagiotis Mouzakis, Fisnik Abrashi and Robert Barr in London, and Shawn Pogatchnik in Dublin contributed to this report.
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Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity
Cell, Volume 154, Issue 1, Pages 61-74, Publication Date 3 July 2013
Copyright ? 2013 Elsevier Inc. All rights reserved.
DOI: 10.1016/j.cell.2013.06.005
Christine?L. Chaffer
Nemanja?D. Marjanovic
Tony Lee
George Bell
Celina?G. Kleer
Ferenc Reinhardt
Ana?C. D?Alessio
Richard?A. Young
Robert?A. Weinberg
Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA
University of Michigan Medical School, Department of Pathology, Ann Arbor, MI 48109, USA
Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Ludwig MIT Center for Molecular Oncology, Cambridge, MA 02139, USA
Corresponding author
These authors contributed equally to this work
The recent discovery that normal and neoplastic epithelial cells re-enter the stem cell state raised the intriguing possibility that the aggressiveness of carcinomas derives not from their existing content of cancer stem cells (CSCs) but from their proclivity to generate new CSCs from non-CSC populations. Here, we demonstrate that non-CSCs of human basal breast cancers are plastic cell populations that readily switch from a non-CSC to CSC state. The observed cell plasticity is dependent on ZEB1, a key regulator of the epithelial-mesenchymal transition. We find that plastic non-CSCs maintain the ZEB1 promoter in a bivalent chromatin configuration, enabling them to respond readily to microenvironmental signals, such as TGF?. In response, the ZEB1 promoter converts from a bivalent to active chromatin configuration, ZEB1 transcription increases, and non-CSCs subsequently enter the CSC state. Our findings support a dynamic model in which interconversions between low and high tumorigenic states occur frequently, thereby increasing tumorigenic and malignant potential.
Source: http://www.cell.com/abstract/S0092-8674(13)00707-1
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<em>Series premieres Wed., May 1 at 8:30 p.m. ET.</em> <strong>What To Know</strong>: Starring J.K. Simmons and Kyle Bornheimer, "Family Tools" centers on a guy who returns home to take over his dad's hardware business when he finds himself jobless.
<em>Season 10 premieres Wed., May 1 at 9 p.m. ET.</em> <strong> What To Know</strong>: This season there will be a "Breaking Bad" themed episode and the crew will tackle myths such as "Are women better than men at multitasking?" and "Which is more sanitary: drying your hands with a hand dryer or a hand towel?"
<em>Series premieres Wed., May 1 at 10 p.m. ET.</em> <strong>What To Know</strong>: Hosted by Kal Penn, this reality competition show will give contestants 30 minutes to solve a daunting engineering challenge.
<em>Series premieres Thurs., May 2 at 10:30 p.m. ET.</em> <strong>What To Know:</strong> The series follows Zach (Bo Burnham), who hires a camera crew to film him throughout his daily life as a part of his quest to become an overnight celebrity ? even though he possesses no real talent. From Zach?s attempts to become a celebrity chef or a ring-tone recording artist to purposefully going missing, he?ll try any avenue to get noticed and stop at nothing until he reaches fame.
<em>Series premieres Thurs., May 2 at 10 p.m. ET.</em> <strong>What To Know:</strong> For the legions who can't say goodbye to "Jersey Shore" just yet, the legacy continues as we follow GTLer Vinny into his sure-to-be-scintillating home life. The premise has random "celebrities" dropping by his house for impromptu interviews -- and Vinny going to visit their homes, too.
<em>Series premieres Mon., May 6 at 10 p.m. ET.</em> <strong>What To Know:</strong> Bravo's new eight-episode docu-series follows four newlywed couples and their most personal moments, from their wedding day to their first anniversary. There's bi-coastal Christian couple Kimberly and Alaska; domestic partners Jeff and Blair, who are 16 years apart; Indian pop star Tina and her modeled-turned-tech-geek husband Tarz; and suburbanites Kathryn and John.
<em>Season 2 premieres Wed., May 8 at 10 p.m. ET.</em> <strong>Where We Left Off:</strong> Because we're all so fascinated by real estate that we could never realistically afford, this show is returning for a second season. C'mon, it's fun to live vicariously.
<em>Season 6 premieres Thurs., May 9 at 8 p.m. ET.</em> <strong>Where We Left Off:</strong> With Season 5 episodes titled "Hillbilly Wipeout," "Gorillas In Our Midst" and "Hotties vs. Nerds 2.0," there can only be more magic in store for Season 6. Viewers of all stripes love watching people hurt themselves in new and remarkable ways.
<em>Series premieres Sun., May 12 at 10:30 p.m. ET.</em> <strong>What To Know:</strong> "Bridesmaids" funnyman Chris O'Dowd stars in Christopher Guest's ("Best in Show") new documentary-style series about a hapless thirtysomething trying to find meaning in his life by tracing his heritage.
<em>Season 4 premieres Sun., May 12 at 9 p.m. ET.</em> <strong>Where We Left Off:</strong> We were hoping that those nails and that hair would be around for another season -- and our wish came true! Theresa Caputo is back, communicating with the dead, for at least another 30 episodes.
<em>Season 2 premieres Sun., May 12 at10 p.m. ET .</em> <strong>Where We Left Off:</strong> Speculation and accusations about the show?s ?reality? aside, ?Breaking Amish? was a hit for TLC. Now, the five Amish and Mennonite rebels, who moved to New York City in the show?s first season, are headed south to Florida ... but trouble seems to follow them wherever they go.
<em>Season 2 premieres Thurs., May 9 at 10 p.m. ET.</em> <strong>Where We Left Off: </strong> In Season 1, we met the owners and employees of JJK Security in small-town Ringgold, Georgia, and Season 2 will offer more insight into the unscripted lives of this unusual group, including Dennis' ongoing journey in his gender transition from female to male.
<em>Season 10 premieres Tues., May 14 at 8 p.m. ET. </em> <strong>Where We Left Off:</strong> After a season of intense competition, Eliana Girard and Chehon Wespi-Tschopp took home first place wins, both for ballet, while Tiffany Maher was the female runner-up for jazz and Cyrus Spencer was the male runner-up for popping/animation.
<em>Series premieres Thurs., May 23 at 9 p.m. ET.</em> <strong>What To Know:</strong> Billed as a unique, original approach to the typical cop drama, "Motive" operates backwards. Each episode starts off showing the victim, and then works its way towards finding the perpetrator and his/her motivations by the end of the episode.
<em>Series premieres Mon., May 20 at 8:30 p.m. ET.</em> <strong>What To Know: </strong> The Fox comedy centers on estranged siblings Henry (Scott Foley), Chloe (Becki Newton) and Jimmy (T.J. Miller) as they attempt to "rediscover their lives" with the money their father left them.
<em>Season 4 premieres Wed., May 22 at 8 p.m. ET.</em> <strong>Where We Left Off:</strong> The home cook competition crowned its third consecutive female winner last season, Christine Ha. Cool fact: She is legally blind. No telling what twists they'll have this season.
<em>Season 4 premieres Thurs., May 23 at 10 p.m. ET.</em> <strong>Where We Left Off:</strong> The last time we saw the cops at 15 Division, they were all in the midst of making some serious decisions about their lives -- including career calls, a possible transfer and, for Andy, a major emotional choice.
<em>Series premieres Thurs., May 23 at 8 p.m. ET.</em> <strong>What To Know:</strong> After a near-death experience, Beth (Anne Heche) is revived only to realize she now has a direct line to God. Of course, her husband Tom (Michael Landes) is skeptical and dismissive -- but when inexplicable things begin to happen, everyone?s beliefs are tested.
<em>Season 9 premieres Mon., May 20 at 9 p.m ET.</em> <strong>Where We Left Off: </strong> Emily Maynard of North Carolina thought she'd finally found love in Jef Holm, but after only being engaged for a short time, they broke up. Here's to hoping "Bachelor" contestant Desiree Hartsock has better luck!
<em>Season 4 premieres Mon., May 26 at 12:01 a.m. PT.</em> <strong>Where We Left Off:</strong> The Bluths are finally back, but there's no telling where and how we'll actually find them. One thing we do know: Each of the nine main characters will have their own episode in this season's 15-episode order, chronicling what they've been up to the last seven years. Some may cross over, but they'll all be complementary -- and they're all meant to set up an eventual "AD" movie. Considering the season will all be available the day it premieres, it sounds pretty perfect for a marathon viewing.
<em>Season 4 premieres Mon., May 27 at 9 p.m. ET.</em> <strong>Where We Left Off:</strong> In the Season 3 finale, Jim (Matt Passmore) proposed to Callie (Kiele Sanchez), even though she passed her board exam and may move to Atlanta. But she didn't respond yet ...
<em>Season 2 premieres Mon., May 27 at 10 p.m. ET.</em> <strong>Where We Left Off:</strong> Did Walt Longmire murder his wife's killer? Season 1 saw flashbacks of the Sheriff of Absaroka County, Wyoming, that would support the theory, but when the FBI asked him in the Season 1 finale, he simply said, "No."
<em>Season 3 premieres Tues., May 28 at 8 p.m. ET.</em> <strong>What To Know:</strong> As in the seasons before it, "Extreme Makeover: Weight Loss Edition" will center on a group of people losing large amounts of weight over the course of a year through diet and exercise.
<em>Series premieres Tues., May 28 at 10 p.m. ET.</em> <strong>What To Know</strong>: The six-part series takes viewers behind the scenes of the Brooklyn District Attorney's office. ADA Kathleen Collins (pictured) is just one of the profiled attorneys. "When you?re on trial, there?s never a day that you really go home and don?t feel stressed," she said.
<em>Series premieres Wed., May 29 at 8 p.m. ET.</em> <strong>What To Know:</strong> Based on a popular British reality competition, this new Jeff Foxworthy-hosted show features 10 home cooks vying for the title of best amateur baker in America, as well as a contract to publish their own cookbook and a $250,000 grand prize. Not bad for a couple of pies work, huh?
<em>Season 3 premieres Wed., May 29 at 8 p.m. ET.</em> <strong>Where We Left Off:</strong> Joe married Russian businesswoman Elena, but then she received a call that prompted her to fly back to Russia to testify for one of her innocent colleagues. The Season 2 finale ended with Mel -- who officiated the wedding -- and Joe toasting to the next "Mrs. Longo," wherever she may be.
<em>Season 2 premieres Wed., March 29 at 8:30 p.m. ET. </em> <strong>Where We Left Off:</strong> Ben and Riley's friend Katie faced some major drama when they found themselves in bed together after a night of partying. The only problem with their little tryst was that Katie was supposed to get married (to someone else) the next day. Luckily, they soon find out that nothing happened, and Riley and Ben share a romantic dance.
<em>Series premieres Wed., May 29 at 9 p.m. ET.</em> <strong>What To Know: </strong> The half-hour comedy clip show, hosted by "Baby Daddy" star Melissa Peterman, features the funniest, most outrageous and memorable dances caught on camera. The dancers from the top two clips of the week compete on stage for a chance to win $10,000.
<em>Season 3 premieres Sun., June 2 at 9 p.m. ET.</em> <strong>Where We Left Off:</strong> Season 2 ended with Rosie Larsen's Aunt Terry being arrested for her murder. Detectives Linden (Mireille Enos) and Holder (Joel Kinnaman) got a call about a new case, but Linden wanted no part of it. Season 3 picks up a year later, with Holder searching for a runaway girl and discovering a string of murders connected to one of Linden's old cases. Though Linden is no longer a detective, she inevitably gets pulled back in.
<em>Season 5 premieres Sun., June 2 at 8 p.m. ET.</em> <strong> Where We Left Off</strong>: The "Housewives" were fractured -- to say the least -- but the aftermath of Hurricane Sandy brings new beginnings for the first ladies of the Garden State. Of course things could certainly go sour yet again.
<em>Series premieres Sun., June 2 at 9 p.m. ET.</em> <strong>What To Know</strong>: The reality series follows six college-educated women from affluent areas of Long Island who are still living with their families.
<em>Season 8 premieres Sun., May 20 at 9 p.m. ET.</em> <strong>Where We Left Off:</strong> Kim and Kanye?s relationship was just breaking the Internet, and now we?ll see it all on screen -- including their baby drama. Khloe?s fertility issues continue, but new ?castmember? Brody Jenner -- Bruce?s son from a previous marriage who is no stranger to reality TV -- looks to be this season?s biggest diva.
<em>Series premieres Mon., June 3 at 10 p.m. ET.</em> <strong>What To Know:</strong> Soapy drama "Mistresses" stars Alyssa Milano, Yunjin Kim, Rochelle Aytes and Jes Macallan as four friends all struggling with different issues in their love lives, with men (including Jason George) and other women complicating matters. And as the title suggests, some of them are flirting with disaster and becoming mistresses themselves.
<em>Series premieres Mon., June 3 at 9 p.m. ET. </em> <strong>What To Know: </strong>This new one-hour drama from executive producer Jennifer Lopez follows a multi-ethnic, blended family, being raised by two working moms, as they welcome another troubled child into their home.
<em>Season 3 premieres Mon., June 3 at 10 p.m. ET.</em> <strong>Where We Left Off:</strong> At the end of last season, Allison broke up with Scott, Peter warned Isaac and Derek that a new pack made up entirely of Alpha werewolves was coming, and said Alphas trapped Boyd and Erica in the woods, leaving viewers uncertain of their fate. Season 3 will pick up four months later, and focus on the introduction of the Alpha pack and the havoc they wreak.
<em>Season 2 premieres Mon., June 3 at 10 p.m. ET.</em> <strong>Where We Left Off: </strong> Throughout Sesaon 1 we got to know Auti, Mia, Tiphany and Chelsie, four women living in Hollywood who also happen to all be in wheelchairs. Season 2 will follow the foursome's new loves and new adventures, including 21-year-old Chelsie's decision to move out of her parents' home.
<em>Season 8 premieres Tues., June 4 at 9 p.m. ET</em> <strong>Where We Left Off:</strong> Last season, traveling dog act Olate Dogs was crowned the winner. This year, a new crop of performers will compete for the $1 million prize. Spice Girl Mel B. and Heidi Klum join the judging panel with Howie Mandel and Howard Stern.
<em>Season 7 premieres Thursday, June 6 at 9 p.m. ET.</em> <strong>Where We Left Off:</strong> In an effort to get more information on Riley, Michael sent Bly to tail her to a meeting with the cartel kingpin, but a cartel member disguised as security blew up Bly's car, killing him and destroying the evidence they collected on Riley. Michael later incapacitated Riley and got her to agree to confess. Then, Fiona, Madeline, Sam and Jesse were released from their prison cells. Michael explained he "did what [he] had to do," but Fiona corrected him, saying, "You did what you wanted to do."
<em>"Graceland" premieres Thurs., June 6 at 10 p.m. ET.</em> <strong>What To Know:</strong> This cop drama, starring Daniel Sunjata and Aaron Tveit, follows a special group of law enforcement agents from the FBI, the DEA and U.S. Customs who all live under the same roof in sunny Southern California. Like frat guys (and girls), but with badges.
<em>Series premieres Thurs., June 6 at 8 p.m. ET.</em> <strong>What To Know:</strong> Dwayne "The Rock" Johnson is producing this competition series to test the strength, courage and integrity of a diverse group of nine individuals. Each week, the contestants will be challenged physically, mentally and morally as they try to prove that they truly deserve the title of "The Hero" and the life-changing grand prize that goes with it.
<em>Series premieres Thurs., June 6 at 9 p.m. ET.</em> <strong>What To Know:</strong> Contestants on this "Survivor"-esque reality show are dropped into the wilderness with only a bottle of water and a GPS device on a mission to find a briefcase filled with $100,000.
<em>Season 2 premieres Fri., June 7 at 10 p.m. ET.</em> <strong>Where We Left Off:</strong> According to series lead Rachel Nichols, Season 2 is all about responsibility. Kiera, Alec and even the terrorists at Liber8 all have to make intense choices that could change the very fabric of their worlds.
<em>Season 8 premieres Sun., June 30 at 9 p.m. ET.</em> <strong>Where We Left Off: </strong> Deb finally learned the truth about Dexter's dark secret, and took a page out of her step-brother's book in the shocking season finale. Can she live with what she did? And can Dexter escape the series without being brought to justice in this final season?
<em>Season 5 premieres Sat., June 8 at 10 p.m. ET.</em> <strong>Where We Left Off:</strong> Our favorite supernatural threesome is back from across the pond for their fifth and final season where they'll finally confront the Devil, once and for all. No biggie.
<em>Series premiere Sat., June 8 at 9 p.m. ET.</em> <strong>What To Know:</strong> The 12-episode British series follows the epic sea journey of the flawed hero Sinbad (Elliot Knight), who embarks on a quest to rid himself of a curse and embrace his destiny. Look for "Lost" alum Naveen Andrews as Lord Akbari.
<em>Series premieres Sat., June 8 at 10 p.m. ET.</em> <strong> What To Know</strong>: The 13-episode first season follows a team of animal experts and scientists that investigate paranormal events.
<em>Season 3 premieres Sun., June 9 at 10 p.m. ET.</em> <strong>Where We Left Off:</strong> Last season ended with the arrival of a new species of alien, and Anne became pregnant with Tom's child. Season 3 will explore whether the new alien is on the side of the humans or has another dark purpose in mind. We'll also learn what happened to Hal while he was unconscious, and what that might mean for the rebellion.
<em>Season 2 summer premiere Mon., June 10 at 8 p.m. ET.</em> <strong>Where We Left Off</strong>: "Switched At Birth" left on a big cliffhanger: Daphne struggled to keep the Carlton School for the Deaf open, John's campaign for office came to a startling halt and Emmett told Bay about Daphne and Noah's kiss.
<em>Season 2 premieres Mon., June 10 at 9 p.m. ET.</em> <strong>Where We Left Off</strong>: Rusty became a ward of the state to the delight of everybody, and Captain Raydor continued to gain the trust and respect of the Major Crimes unit.
<em>Series premieres Mon., June 10 at 10 p.m. ET.</em> <strong>What To Know:</strong> Based on author David Baldacci?s bestselling private eye series, Rebecca Romijn and Jon Tenney star as the titular former Secret Service agents now working as private investigators who aren?t always by-the-books.
<em>Season 4 premieres Tues., June 11 at 8 p.m. ET.</em> <strong>Where We Left Off:</strong> Red Coat, who looked a whole lot like Ali, saved Emily, Aria, Hanna and Mona from a fire, while Spencer looked on in shock. The first episode of Season 4 is titled "A Is For A-L-I-V-E" and <a href="http://www.eonline.com/news/394204/spoiler-chat-scoop-on-pretty-little-liars-once-upon-a-time-revolution-new-girl-and-more" target="_hplink">E! News reports that viewers will meet Marion, Toby's mother</a>, who was <a href="http://www.huffingtonpost.com/jaimie-etkin/pretty-little-liars-recap_b_2673316.html" target="_hplink">revealed to be dead in Season 3, Episode 18, "Dead To Me."</a> "All of the questions fans have will be answered," <a href="http://www.wetpaint.com/pretty-little-liars/articles/pretty-little-liars-star-sasha-pieterse-dishes-on-season-4-questions-will-be-answered-exclusive" target="_hplink">star Sasha Pieterse told Wetpaint Entertainment recently</a> of Season 4.
Source: http://www.huffingtonpost.com/2013/07/23/supermarket-superstar-premiere-video_n_3637889.html
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Fixes:
- Added support Windows XP x64 Edition for ThinkPad W530.
- Changed the software name to Intel Management Engine Interface 8.0 and Serial Over LAN (SOL) Driver
- Added support for ThinkPad X1 Carbon.
Versions:
- 8.0.3.1427 Package
- 8.0.0.1262 Management Engine Interface
- 8.0.0.1262 Serial Over LAN (SOL) Driver
- 8.0.3.1427 Local Manageability Service (LMS)
- 8.0.3.1427 Intel Management and Security Status (IMSS)
- 8.0.3.1427 User Notification Service (UNS)
- 1.2.22.0 Intel IPT Client Middleware
This package installs the Intel Active Management Technology (AMT) Manageability Engine components Drivers to enable the following device:
- Intel Active Management Technology - Serial Over LAN (SOL)
It is highly recommended to always use the most recent driver version available.
Do not forget to check with our site as often as possible in order to stay updated on the latest drivers, software and games.
Try to set a system restore point before installing a device driver. This will help if you installed a wrong driver. Problems can arise when your hardware device is too old or not supported any longer.
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